Male mouse pregnancies leading to human male birth: biotech experiment
Surgically attach a pregnant female rat to the uterus-transplanted male rat, so that her "pregnant blood" nourishes the male pregnancy like an elixir. Objective: the business of trans pregnancies, defined as a "human right"

Share this article

What good could it do to take a male mouse and a female mouse, surgically attach them like Siamese twins parabiosis-, connect the two circulatory systems to make the blood of the female flow into the male, castrate the male, transplant a uterus into her body, artificially impregnate the female, also insert embryos into the uterus of the male mouse and carry out the two pregnancies until both were delivered by cesarean section?

It certainly doesn't serve the purpose of giving birth to male mice or male lambs or oxen or male specimens of other mammals. Instead, it serves to experiment - with great suffering to these creatures - the possibility of human male pregnancy.

The goal is this - and has always been this since the dawn of time -: taking on pregnancy, taking on maternity, finally being able to do without women except as suppliers of oocytes and "pregnant blood", apparently a true elixir for the pregnant male. And it obviously serves to build a great business intended for MtF trans people or simply to any man who wants to experience pregnancy for autogynephilic fetishism.

The experiment was conducted in China by Rongjia Zhang and Yuhuan Liu, has not yet been peer-reviewed and appears in preprint on the Biorxiv website. Is called A rat model of male pregnancy, Male pregnancy rat model. You could also just call it Womb envy, the sacred cup, the Grail of all time.

The study reads, among other things:

We constructed a male rat pregnancy model with a four-step strategy: a heterosexual parabiotic pair was first produced by surgically uniting a castrated male rat and a female rat. The uterus transplant (UTx) was then performed on the male parabiont 8 weeks later. After recovery Blastocyst stage embryos were transplanted into the grafted uterus of the male parabiont and into the native uterus of the female parabiont. Cesarean section was performed at embryonic day (ED) 21.5.

Parabiosis is an experimental model that can surgically connect two animals and share their blood microenvironment through the anastomosis… to obtain the female-like microenvironment through blood exchange... to observe embryonic development in the uterus grafted into the male parabiont below exposure to pregnant blood.

The selected female rat was used for two different roles: as uterus donor; as a female parabiont for heterosexual parabiosis surgery. Before the parabiosis operations, the male's testes, epididymis, right ventral prostate and seminal vesicles were removed.

A total of 842 blastocyst stage embryos were transferred to 46 heterosexual parabiotic couples per embryonic day (ED) 4.5 (562 embryos transferred to female parabionts and 280 embryos transferred to male parabionts). At ED 18.5 one was performed exploratory laparotomy to observe the development of the transferred embryos. We found that 169 (30,07%) embryos developed normally in native uteri of female parabionts at 18.5 ED, while only 27 (9,64%) embryos developed normally in grafted uteri of male parabionts.

We therefore deduced that Transplanted embryos can develop normally in grafted uteruses of male parabionts only when the female parabionts conceive and provide pregnant blood exposure to the male parabionts. 

We constructed a male pregnancy model in the rat and found that transplanted blastocyst-stage embryos can develop to maturity in engrafted uteri of male parabionts if the male parabionts are exposed to pregnant blood from female parabionts. The success rate of the entire experiment was very low, but 10 pups were able to be delivered by male parabionts by cesarean section and developed to adulthood. Furthermore, we found two new phenomena in our rat male pregnancy model. 

First, during cesarean section at ED 21.5 were observed abnormal stillbirths only in the grafted uteri of male parabionts. Considering that no abnormalities were found during laparotomy at ED 18.5, it was inferred that the abnormal death of fetuses in male parabionts began at the late stage of embryonic development (approximately at ED 18.5–21.5). Whether this phenomenon is peculiar to male pregnancy in mammals remains unknown. Secondly, only embryos exposed to pregnant blood from female parabionts can develop normally into male parabionts, suggesting that the normal development of embryos in male mammals relies on a mechanism that can be induced by exposure to pregnant blood rather than by exposure to female blood.

For part of the transgender movement and other programs for the creation of new family structures, male pregnancy is one human rights issue. As stated in the Journal of Medical Ethics:

From the point of view of justice, there ismoral imperative to ensure equitable access to UTx [uterine transplant]. Arguments against providing UTx to genetically XY [transgender] women that are unrelated to safety and efficacy should be carefully evaluated to address the potential discrimination against genetically XY women as a social group.

Therefore a question of "social justice" would legitimize this type of research because it is absolutely believed It is unacceptable that a person who decides to transition from masculine to feminine - with cosmetic adaptations of his body, which in any case remains an of motherhood.

While apparently the fact that women are understood as suppliers of oocytes, uteruses and even "pregnant blood" does not create any ethical problem. In essence, freely parasitized female bodies from male bodies. It remains to be understood how and with which devices this continuous transfusion of female blood into a male body could be achieved.

Daily transfusions? Vampirizations? Blood trade? Will needy women be able to think about getting themselves pregnant so they can sell their surrogate pregnant blood, as well as their eggs and uterus?

There is also the problem of having procured one severe suffering to helpless animals without any justified and compelling reason other than the possible business.

As the intelligent friend who reported the experiment to me notes, if we invoked the defense of animal rights we would probably have a better chance of stopping this horror than we would have if we asked to consider women's rights - and those of girls and boys -, never so little considered in modern times as in this painful end-patriarchy .

Marina Terragni


Share this article
Scroll to Top